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ALICE E STANTON
| technology towards treatments: at the interface of technology and biological discovery
miBrain
Incorporating the 6 Major Brain Cell Types
Each of the major brain cell types differentiated from human
patient-specific iPSC lines.
Human Brain Tissue Hallmarks
3D integral Immuno-Glial-Neurovascular Units
Capturing Cell-Cell Interactions
Across cell types to include important mechanisms in physiology and disease pathogenesis.
Disease Modeling Across Phenotypes with Patient-Specific Human Cells
For example, modeling APOE4 risk for Alzheimer's Disease.
Enabled by Neuromatrix Hydrogel
Dextran-based biomaterial incorporating brain tissue proteoglycans and basement membrane-mimicking peptides.
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